Enterprise UK and Unleashing Enterprise have appointed Lava PR following a three-way pitch.
The agency has secured a place on Enterprise UK's regional roster, reporting to regional PR manager Rachel Burkitt.
At the same time the agency has been appointed as sole PR consultant to Unleashing Enterprise, an initiative funded by East Midlands Development Agency, and managed by Prevista.
The consultancy reports to Prevista regional manager Chris Shaw.
Lava managing director Matt Hammerton said: 'It is a complicated brief and sees us working with two clients under one agreement.
'There is a great deal of synergy between Enterprise UK and Unleashing Enterprise, so it makes sense,' he added.
Unleashing Enterprise is creating a partnership for all enterprise educators to pioneer a culture of enterprise across the East Midlands.