The agency will seek to build up the profile of Glam Media, the company behind lifestyle and entertainment websites Glam.com and Brash.com.
Global analyst ComScore says Glam Media is the 16th biggest web property in the UK, ahead of the Daily Mail, Sky and Tesco websites. It was launched in the UK in June 2008 and reaches 12.4 million users nationally and 64 million worldwide.
Glam Media competes with handbag.com, ivillage and Glamour.com. It is split into Glam.com for women and Brash.com for men.
Brands2Life won the account after a three-way pitch and will primarily run a b2b media relations campaign to educate people about Glam Media. It will mainly target advertisers and publishers.
Giles Fraser, MD of Brands2Life, said the message would be that while most internet sites did not have a lot of quality control on ads or editorial, companies that advertise through Glam Media need not worry about risking their brand reputations.