The Liverpool Culture Company's director of comms Paul Newman will join the North West media hub in October as head of communications. Lisa Hill and Helen Johnson will complete the comms team.
Media City UK will be home to over 2000 BBC staff from 2011. It claims it will be the largest dedicated media community in the UK.
The marketing budget for Media City UK is estimated to be in excess of £1m per year.
Newman is a former Football Association director of comms who handled media for the re-development of Wembley Stadium and the 2002 World Cup.