The agency's Manchester office will help the region conduct its biggest-ever poll to find out why it has one of the biggest drink problems in the country.
Slam has already launched the Big Drink Debate from Coronation Street's Rovers Return Inn, with the show's Kym Ryder joined by NHS regional director of public health Dr Ruth Hussey.
The agency has also achieved on-screen poster placement on the sets of Coronation Street and Hollyoaks, plus coverage on BBC One's Politics Show.
In the North West, 73,000 crimes a year are linked to alcohol and one person is admitted to hospital every seven minutes with an alcohol-related condition.
The three-month campaign is being launched by NHS North West's Our Life programme in partnership with Government Office North West. It will aim to identify how people use alcohol and canvass their views on how it affects health and wellbeing.