DADA was awarded the account following a five-way pitch.
The Glasgow-based drinks firm has brands including Whyte & Mackay Blended Scotch Whiskies, The Dalmore Single Malt, Jura Single Malt and Vladivar Vodka.
The agency is tasked with handling all the UK-wide activity as part of the six-figure account.
DADA MD Oli Norman said: 'Technology and travel links are continually bringing major cities in England and Scotland closer together and this opens up the traditionally London-centric PR market onto a national scale.'
DADA has also been hired by Domino’s Pizza to manage its PR activity across its Scottish franchise network.