Youth specialist Making Waves has been appointed by the trust - the only charity in the UK to focus solely on the disease - to oversee the campaign, badged ‘What not to share'.
Making Waves is planning a music tour of UK universities this summer, which will aim to raise awareness of Hepatitis C and the ways in which it can be spread.
The agency's senior project manager, Dawn Newman, said people in their twenties were one of the most-at-risk groups.
‘Most young people are unaware of the different ways in which Hepatitis C can be passed on,' said Newman, who joined the agency from Shine Communications at the end of last year. ‘As well as sharing banknotes to snort drugs, sharing razors or toothbrushes can also spread the disease.'
The trust has created a MySpace profile for the campaign, and will target other online social media as well as student publications and music titles.
Last month, Body Shop founder Dame Anita Roddick was diagnosed with the disease. She has since become a patron of the trust.