Hotwire takes over from Edinburgh-based Scot PR, which had run the account for five years.
‘I believe the change was prompted by a desire to work with a company that had a network of offices and associates around the world,' said Scot PR director Scott Thornton.
London-based Hotwire has been retained to co-ordinate a multi-country media relations campaign. It will also implement a UK campaign targeting the business and technology industries.
Edinburgh-based Axios employs around 200 staff across nine countries.