The charity will run a six-week ad and PR campaign from 14 May targeting children's and youth media.
NSPCC director of comms John Grounds said: 'We will talk to as many young people as we can through radio programmes, magazines, internet sites and other media.
'Visitors to teen websites such as MyKindaPlace, Habbo Hotel and Girland will find real-life stories, advice and online chat. Other magazines and radio programmes will run features and advice.'
The NSPCC says one in six children will suffer some form of sexual abuse before the age of 16, but three-quarters will keep it secret.