The NDA went live on 1 April to take responsibility for the decommissioning of 20 nuclear sites across the UK safely and speedily.
BPC sealed the contract this week after a competitive pitch. Chime PR division chairman Kevin Murray will lead the account, supported by the agency's public affairs and corporate and financial divisions.
The appointment comes as Hamilton prepares to join the NDA next week as head of comms. He will oversee a seven-strong media team based in Cumbria. Hamilton, who quit TfL in March, is also a former director at Grayling and public affairs director at Safeway.
He reports to director of comms Jon Phillips, who said the NDA 'has the objective of open and transparent engagement with its stakeholders built into its statutory requirements'.
Bell Pottinger Public Affairs director Tim Walker and Corporate & Financial director Mark Herbert are also servicing the account, worth close to £100,000.
Hill & Knowlton, Media Strategy and Taylor Keogh Communications also pitched.
The agency will keep the Government, trade unions, local authorities and NGOs abreast of the clean-up operation, which has an annual budget in excess of £1bn.