Featuring celebrity interviews and health tips in a glossy format, Your Life! is free and will include eight pages of information on local NHS services.
More than 70 PCTs have co-operated with independent healthcare information provider Dr Foster to produce the magazine.
The first issue includes an interview with rap star Ms Dynamite about her life after giving birth and actress Amanda Mealing about her battle with breast cancer.
Your Life! will appear in 63 different editions, available on NHS premises and at newsagents, high street retailers, hairdressing salons and nail bars.
‘We’re open to suggestions, but we will make sure any content is in keeping with the values of the NHS brand,’ said an NHS spokeswoman.