The agency will work alongside Exeter-based RH Advertising on the campaign for the South West Regional Development Agency, South West Tourism and the South West Regional Assembly, aimed at attracting businesses and visitors to the region.
The first phase of the three-year campaign, including a media launch next month, will be aimed at potential UK investors in sectors such as technology and aerospace, with a smaller emphasis on tourism.
The campaign will also highlight those who have already chosen to relocate to the area, such as the Met Office. Its new £80m HQ opens in Exeter later this year.
A second phase of the campaign aimed at a wider international audience is expected in September.