The news follows the recent departure, revealed by PRWeek last month, of Hotwire's global chief operating officer and EMEA head Alex MacLaverty.
Hotwire said in a statement this afternoon: "We're excited to report that after five years in the deputy MD then MD role, Matt Cross is taking the next step in his career with a promotion to the newly created role of head of B2B, EMEA. From 1 April, Matt will be focused on attracting, winning and retaining our B2B clients across the region.
"This change also brings about the opportunity to think about our UK leadership and we're delighted to say that a new UK MD will be joining Hotwire within the next three months. After a significant search, we've found a really fantastic candidate and we're very close to being able to tell you all about them. As soon as notice periods and communications at their current firm are sorted out, we'll reveal all."
In January, Hotwire hired Chris Paxton as global chief strategy officer, joining from consultancy The Leading Edge, where he was EMEA CEO.
Global CEO Barbara Bates told PRWeek in January that Hotwire is on track to beat its organic and broader business growth targets for the year after picking up several global clients and building its strategy and insights division.
The agency has 15 offices and 250 staff across the world, including in London, New York, San Francisco, across Europe, Dubai, Sydney and Brazil.