The campaign, which launches today, is part of the mental health programme Time to Change. All PR surrounding the campaign will be handled by the charities' in-house comms teams, with support from creative agency Latimer.
A £660,000 investment from the Department of Health will see Time to Change deliver a national social marketing campaign and work alongside the charity Young Minds to deliver training in 30 schools across three areas in England.
The campaign will target young people and parents to raise awareness of mental health problems and the stigma that many teenagers face.
Care minister Alistair Burt said: "I am proud to announce the biggest transformation to young people’s mental health and one of the greatest investments the sector has seen.
"The largest ever national anti-stigma campaign for young people and their parents will launch next month. We will be working alongside Time to Change on a campaign specifically targeted on the places where young people spend their time online."
Sue Baker, director of Time to Change, said: "With three children in every classroom experiencing mental health problems, and the latest ONS figures showing one in eight children aged 10 to 15 reporting symptoms, we have to create a new era of openness and support.
"We have already seen significant attitude and behaviour change among adults in England, and we've seen positive results from the work we’ve been doing with children and young people and schools in recent years, but this campaign will drive new conversations across England with 14- to 18-year-olds and parents, through a high-profile national campaign and an in-school programme that we will be delivering with Young Minds."