The company, which claims to be the world's largest provider of flexible offices and is valued at over £3bn ($4.6bn), currently works with agencies on a regional basis but has no overarching global agency for this work.
The firm operates in 106 countries globally and operates through several brands including Spaces, Kora and Regus Express. It also has a growing business in workplace disaster recovery.
The decision to take on a global agency follows the appointment of London-based global corporate affairs director Emma Gilpin-Jacobs, who arrived at the organisation in April.
Gilpin-Jacobs, who is leading the search, is best known for her seven years heading global comms at the Financial Times Group, a role she left in 2013. She has also since worked for British politician Nick Clegg and UK train booking firm Trainline.