Sophie Smith and Megan McGonigle will rely on the agency’s brands for food, clothing and entertainment.
The two will even use client products for accommodation, sleeping at the office in a tent and sleeping bags from The North Face.
The project will be streamed live online, through webcams in the Brazen office.
Smith and McGonigle said they would also invite celebrity guests to join them for office-based events during the campaign. They have yet to confirm who the guests will be.
McGonigle said: "The job market is flooded with young professionals determined to get noticed, with every CV claiming that candidates ‘go the extra mile’ for their clients. But how many of them prove it?"
Brazen CEO Nina Webb said: "At Brazen we pride ourselves on being creative and being the best. I’ve always encouraged my employees to be Brazen through and through so I’m incredibly proud of Sophie and Megan for doing just that."
The week-long campaign starts on Monday 23 March, and can be followed on Twitter using the hashtag #PRLife.