Tea brand PG Tips got its monkey mascot involved, with a Red Nose Day challenge to climb the Shard, the UK's tallest building.
Persil gave its laundry detergent packaging a Red Nose Day makeover, with four special edition products featuring characters Perry, Penny, Percy and Posey. The brand asked Twitter users to make their faces funny and share their pictures on Twitter.
Make-up brand Rimmel created a Red Nose Day edition of its red lipstick, with £1.67 from each sale going towards Comic Relief. Kate Moss fronted the campaign and rather than the brand's usual 'Get the London Look' slogan, it asked social media users to 'Get the Red Nose Look', encouraging people to share their pictures.
Specsavers helped raise money for the cause by asking customers to buy its Red Nose Day 'funny specs', donating £1 from every pair sold.
Mini Babybel brought in reality TV star Joey Essex for its Red Nose Day campaign, with a PR stunt to make unsuspecting members of the public laugh.
A supporter of the cause since 1999, Sainsbury's promoted its Red Nose Day merchandise, including a range of nine different red noses, with at least 60p from every sale going to the cause.