The inaugural event will take place on 5 October with 12,500 entrants starting and finishing the course at the O2 Arena.
Brando, Sony Ericsson's retained agency will use the event to promote the firm's W760i phone handset.
Brunel University lecturer Dr Costas Karageoghis has selected songs that he claims are 'scientifically' selected to boost performance.
Brando will seed handsets with celebrity and journalist runners, handle interviews with Costas and media relations.
It will also run a competition to find a band to play to the runners at one point during on the route. Other retained agencies Iris and Mediaedge:cia will also be involved in the event.