The RCN was unable to confirm whether Egan had a new job to go to, or to comment on the circumstances surrounding her departure last month.
The head of media position will now be job-shared by media officers Colin Beesley and Rachel Duston until a permanent replacement is found.
Head of communications Amanda Callaghan said the charity was aiming to have a new person in place by the end of the year.
Egan joined from the Medical Research Council in summer of last year (PRWeek, 25 June 2005), filling the role left vacant by Eileen Philips's departure to the General Medical Council.
The RCN is the largest nursing union in the world. The head of media's responsibilities include retaining media interest in the organisation's campaigns and raising the profile of chief executive Beverly Malone, due to stand down in the autumn.
Callaghan said Beesley and Duston would handle day-to-day running of the ‘Keep nurses working - Keep patients safe' campaign (PRWeek, 19 May). They will also be handling publicity campaigns surrounding the upcoming party conferences, she added.