Dubois-Dumee will stand down from the role he has held for 15 years at the end of October.
He was unavailable for comment as PRWeek went to press, but sources say the 59-year-old is leaving to pursue other interests.
Dubois-Dumee joined Renault in 1978 after a stint leading rival Citroen's press office.
He started at Renault as head of the press office, moving up the ranks to director of external relations, then director of information and PR before assuming his current role as senior vice-president of corporate communications.
From 1 November, Renault director of corporate information Patrick Bessy will take over the job at the helm of the group's 350-strong global communications department.
Bessy will report directly into Renault executive vice-president, chairman and CEO of the Renault Formula 1 team Patrick Faure.
The PR role oversees Renault's corporate communications team of 90 in the Boulogne HQ, alongside up to 250 communicators across the globe.
Renault corporate comms manager Marie de Saint-Cheron said: 'Renault's communications strategies and the firm's communications networks across the world are organised from the French headquarters, overseen by the senior vice-president.'
She added the communications department is organised into three divisions: PR, handling events, motor shows and corporate partnerships; information, overseeing internal and external communications alongside media relations; and international co-ordination and strategy planning.