Osborne delivered his statement to the House of Commons at lunchtime - the full document was then published online.
Reducing the UK's debts and deficit was a major theme, resulting in cuts to several government departments, although NHS spending will be £10bn higher in real terms in 2020-21 than it was in 2014-15, Osborne announced.
Another area to see substantial investment was the Government's digital capability. The statement says: "The Spending Review invests £1.8bn in digital technology and transformation projects across the public sector over the next four years, cementing the Government’s position as a digital leader. The Government Digital Service (GDS) will continue to act as the digital, data and technology centre for government."
The GDS itself will receive £450m to "create common platforms, for example GOV.UK Pay, which will simplify hundreds of different payment systems making it easier for businesses and citizens to pay government".
However, Osborne pledged tighter controls on government comms spending, with his statement saying: "In the last Parliament the Government introduced tight controls over non-essential spending, including advertising and marketing, consultancy and IT. In this Parliament the Government will go further by moving to a centrally managed budget for communications campaign spending from 2016-17."
Away from comms, the biggest headline from the statement was Osborne's announcement that he would abandon controversial cuts to tax credits – closely followed by the news that there would be no reduction in police budgets.
In his response to the Chancellor's statement, shadow chancellor John McDonnell said: "I'm glad he's listened to Labour and seen sense." However, some journalists commented that this actually conversely represented a lost PR opportunity for Labour.
Osborne U-turn kills off Lab's political attacks on tax credits, will more generous than expected police funding kill off that attack too?— Laura Kuenssberg (@bbclaurak) November 25, 2015
Tax credits U turn whopper victory for Lab - but sadly for Labour, it reflects Tory view Corbyn weak enough for them to get away with it— Allegra Stratton (@BBCAllegra) November 25, 2015
McDonnell's response also provided one of the more bizarre Autumn Statement moments of recent years - which was enjoyed by Twitter users, many of whom as ever reacted in real time to Osborne's statement via the social network.
Pretty sure I wouldn't advise anyone to get out Mao's book at the dispatch box. Even in jest.— Andrew Ross (@AJMRoss) November 25, 2015
If you’re a hack just tweeting lines from Osborne’s address, stop. I’ve got it on, as will anyone else interested enough to be on Twitter— Luke McGee (@lukemcgee) November 25, 2015
Sorry for all these respectable family firms that are hoodwinked into hiring PRs to churn out press releases noone uses on Autumn Statement— Matthew Holehouse (@mattholehouse) November 25, 2015