The agency, which has its official launch in March, has an initial client list that includes BBC Children In Need, the Jamie Oliver Food Foundation and the Eva Longoria Foundation.
Ede said the new agency would draw on his 17 years of experience working with the charity sector. Among the charity campaigns Ede has previously worked on are Balls to Cancer, Jeans For Genes and MTV Staying Alive.
Ede will be joined by Rosie Stewart, who works with him at EdenCancan, as campaigns manager and Emma Gosney.
The new agency also wants to work with businesses to help them create and execute CSR initiatives. It will offer strategic support, strategic philanthropy and cause-related marketing communications among its services.
Ede said: "I believe East of Eden can make charity accessible, interesting and engaging by creating great campaigns that build awareness and talkability and in turn raise a lot of money for good causes."