After consultation with a number of agencies, the foundation has appointed PrettyGreen to promote and develop the creative comms and ambassador activity around the annual Movember moustache-growing campaign.
Meanwhile Ketchum will promote the Movember Foundation as a year-round men's health charity funding programmes around the world in the areas of prostate cancer, testicular cancer and men’s mental health.
Both agencies will work together closely, reporting to head of comms and PR Paul Mitcheson.
The foundation previously worked with Freuds.
A spokeswoman for the foundation said: "The Movember Foundation and Freud Communications have created a number of innovative and memorable campaigns over the past few years, but in the spring we took the decision to work with different charitable agencies and organisations respectively.
"This is a great opportunity for us to work with new agency partners and we’re excited about the potential these relationships bring to our mission to change the face of men’s health."