The charity has hired Forster Communications as it seeks to leverage a series of moves clamping down on the use of animal testing within the EU.
Eloise Shavelar, campaign manager for the RSPCA, pointed to the complete ban on the sale of cosmetics developed through animal testing that was introduced in March.
"This is the latest in a series of bans across the EU and represents the closing of a final loophole," she said.
"However, this doesn’t mean products in the EU are produced by cruelty-free companies, as some may still be testing on animals elsewhere in the world."
Shavelar explained that the one-year brief, which followed a pitch, would see Forster working with the charity to "springboard off the ban" in an effort to persuade companies to stop such testing beyond the EU.
This will include initially approaching cosmetics companies about their practices before focusing on getting media influencers and the consumer to apply pressure.
"This will involve everyone from RSPCA supporters through to influencing beauty bloggers," she added.
Last month PRWeek revealed that the charity was mapping out a ten-year strategy as it attempted to broaden public understanding of its work.