Jeremy King, currently editor of Haymarket magazine Event and Media Week, will take up the role in December.
The role was created following a review of senior management team posts across the business. King's role replaces a comms manager post formerly held by Stephen Farmer.
'The biggest challenge is to give the O2 personality without taking away any of its success,' said King.
King is expected to create a comms strategy for the venue, which was put up for sale by Anschutz Entertainment Group in September.