The brand is part of leisure travel group TUI Travel, and is a specialist tour operator offering long-haul scheduled tailor-made holidays.
The upmarket brand's portfolio offers more than 40 destinations from Antigua to Zambia.
JPR was launched in January, and is run by Jess Hilliard and Jemima Stiles.
The agency won the account following a competitive pitch.
Thomson Tailormade joins a client roster at JPR that includes Croatian National Tourist Board.
Last month, Bondy Consulting picked up a brief with TUI to work on its Thomson and First Choice brands. The agency was hired without a competitive pitch to work on strategic and product level activity.